EucoHIV collects anonymous clinical and laboratory data of patients treated with maraviroc into a central repository. Analyses on these data will give important insights into the clinical utility of HIV tropism testing and coreceptor antagonist usage in antiretroviral therapy.
Data collection for the repository is coordinated by the University of Liverpool in the United Kingdom. Submission of case records is reimbursed.
An integral part of the project is to make the EUCOHIV database available for research proposals upon submission of research proposal. The database is hosted as an extension of the EuResist database and academic/public researchers can submit proposals for research studies. Each request will be processed first by the EUCOHIV Board and, if the project is feasible, ethical and scientifically sound, the proposal will be circulated to all members of the Study Group for approval. Whereas we hope that the initiative may progress through consensus, members of the Study Group can opt out of a proposed analysis and ask for their submitted data to be excluded from that specific proposal.The role of all data providers will be acknowledged in all presentations and publicationsetc…..
As a further warranty, each contributor reserves the right to have its data permanently deleted from the database at any moment without the need to justify this decision.
The first round of data collection has been closed in September. The Database is now open for analysis.
Participation in the database
Please note that the EucoHIV database is closed.
It is no longer possible to submit your data collection.
The submission of study proposals is open now.
The study group seeks submission of scientific proposals for analysis from all participants and the scientific community at large.
You are invited to submit your proposal.
Download here the proposal form and send it to firstname.lastname@example.org. You will receive an answer to your proposal within four weeks.
In the first instance contact one of the members of the Steering Comittee about the proposed analysis so they may give feedback on feasibility.
The EucoHIV database is closed.
Data received from contributing centres are imported into a central database. A database has been developed to hold the data required for EucoHIV as an extension of the EuResist Integrated Database (EIDB). The database holds all the information planned to be part of the EucoHIV dataset including patient demographic and clinical data and virus envelope and pol gene sequences.
All data will be held anonymously.
Each participating centre will be free at any time to withdraw own data from the whole study or from specific proposals for analysis without the need to provide a justification.
Please note submission for analysis proposals is open.
Now the first round of data collectionhas been closed for submission you are invited to submit proposals for analysis.
We hope to re-open data collection in 2016.
Data sharing policy
The Steering Committee wished to encourage proposals for analyses of the dataset, which seek to address scientific questions in line with EucoHIV mission statement. Any researcher affiliated or with links to a participating centre contributing data is entitled to submit a proposal and is encouraged to initially have an initial informal discussion with a member of the Steering Committee. An outline proposal form can be downloaded here
EucoHIV will setup and run periodical quality assurance programs for gp120 sequencing for Sanger and ultra deep sequencing.